(P 347) SURVIVAL ANALYSIS AND PROGNOSTIC FACTORS OF SOFT TISSUE SARCOMAS OF THE TRUNK AND EXTREMITIES TREATED BETWEEN 2010 AND 2015: EXPERIENCE OF THE BRAZILIAN NATIONAL CANCER INSTITUTE

Objective: To evaluate the five­year overall survival (OS) of patients with soft tissue sarcomas (STS) located in the trunk and extremities, who underwent surgical treatment at the National Cancer Institute (INCA).

Methods: A retrospective cohort study conducted between 2010 and 2015, analyzing survival rates and clinicopathological characteristics. The statistical tests log ­rank, Cox regression, and chi­square were applied.

Results: A total of 223 patients were included, of whom 106 (47.53%) were men and 117 (52.46%) were women. Patients with high grade tumors had a significantly lower five­ year OS compared to patients with low ­grade tumors (HR = 5.21; 95% CI: 3.11–8.73). Patients with tumors < 5 cm had better OS compared to those with tumors ≥ 5 cm (HR = 1.99; 95% CI: 1.12–3.54). Patients in stages III and IV had an OS at least four times lower. No significant differences were observed regarding other prognostic factors.

Conclusion: The five­ year OS data, along with the clinico pathological characteristics and follow­up details, helped to outline an epidemiological profile of patients with STS undergoing surgical treatment at INCA, with results comparable to those found in the biomedical literature.