(P 383) MULTIDISCIPLINARY TREATMENT OF INGUINOSCROTAL SARCOMAS: ANALYSIS OF 39 CASES TREATED BY SURGICAL APPROACH

Objective: Inguinoscrotal sarcomas are a rare sarcoma subtype. Treatment of choice is radical inguinal orchiectomy with wide local resection of surrounding soft tissues. However, consensus regarding prognostic factors is lacking. We present our experience at a referral sarcoma centre regarding the management, oncologic results, and prognostic factors.

Methods: We conducted a retrospective analysis of patients who underwent surgery for inguinoscrotal sarcomas between 2005 and 2023 at a sarcoma referral hospital.

Results: The study included 39 patients. The most frequent histology was liposarcoma. Seven patients required surgical reconstruction with a microvascularized free flap. Four patients presented major postoperative complications. Mean follow-up was 46 months. Overall survival rates were 97.4%, 81.7% and 64.8% at one, three and five years. High-grade tumours were correlated with worse overall and disease-free survival.

Conclusion: The chance finding of a sarcoma in the inguinal region poses a diagnostic and therapeutic dilemma when considering options for treatment with curative intent. Vascular and muscle resection followed by vascular and/or free flap reconstruction may be necessary to achieve complete surgical resections, therefor a multidisciplinary approach is needed. A preoperative biopsy should be performed to establish the histological grade, which may be a main prognostic factor.