Associate Member
St. Jude Children's Research Hospital
Elizabeth “Beth” Stewart, MD
Dr. Stewart is currently an Associate Member in the Department of Oncology at St. Jude Children’s Research Hospital. She originally came to St. Jude in Memphis as a clinical fellow in 2010, and she joined the faculty after completing her Hematology-Oncology Fellowship training in 2014 while working in the laboratory of Dr. Michael Dyer. As a fellow, Dr. Stewart discovered new drug combinations using PARP inhibitors that were effective in Ewing sarcoma—and this finding was translated to several clinical trials for relapsed pediatric solid tumor patients.
Today, Dr. Stewart splits her time between running her own research lab as well as caring for children with high-risk sarcomas. Her research focuses on generating advanced preclinical modeling systems to understand the molecular and cellular mechanisms of disease recurrence. She played an integral role in founding the Childhood Solid Tumor Network, the world's largest and most comprehensive collection of pediatric solid tumor resources and orthotopic patient-derived xenografts which are made freely available to the scientific community. She is the principal investigator for a U01 grant which focuses on testing novel drug combinations for rhabdo and non-rhabdo soft tissue sarcomas and she is also funded by the FDA to generate novel 3D/2D culture systems to study the impact of the tumor microenvironment on the response to therapy.