(P 390) USE OF DERMAL TEMPLATE FOR NERVE PROTECTION IN LIMB-SPARING SURGERY FOR SOFT TISSUE SARCOMAS: PRELIMINARY EXPERIENCE FROM INSTITUT BERGONIE

Objective: In limb-sparing surgery for soft tissue sarcomas, large nerve exposure is common and poses risks of neuropathic pain and functional impairment. Optimizing reconstruction is a cornerstone of postoperative recovery.

Methods: Between 2023 and 2025, we conducted a retrospective and prospective analysis of 10 patients undergoing limb sarcoma resection at Institut Bergonié. A dermal regeneration matrix (Matriderm®) was applied to protect exposed peripheral nerves and assist in soft tissue reconstruction. Outcomes included DN4 questionnaire scores for neuropathic pain, analgesic consumption, and functional evaluation using the MSTS score.

Results: Preliminary results indicate effective nerve protection, a reduction in neuropathic pain (lower DN4 scores), decreased analgesic use, and favorable early functional outcomes. Few matrix-related complications were observed.

Conclusion: The use of dermal matrices in complex sarcoma surgery may improve both pain control and functional recovery. This approach warrants further investigation in a larger cohort, with stratification based on pre- or postoperative radiotherapy to assess its influence on integration and outcomes.